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Justin Julander

Profile Picture

ADVS

Virology, Antiviral Research

Research Associate Professor






Contact Information

Office Hours: 9:00AM - 5:00PM
Go toOffice Location: VSB 305
DialPhone: 435-797-7215
SendEmail: justin.julander@usu.edu

Awards

Graduate Research Mentor of the Year, 2017

ADVS department

Hightlighted article, 2016

Antiviral Research

Highlighted Articles in Antiviral Research, 2014

Elsevier

    Publications - Books & Book Chapters

      Books

    • Julander, J., Mutton, N., Birch, P., (2013). The complete Children's python: a comprehensive guide to the natural history, care, and breeding of Antaresia species. ECO/ Serpent's Tale *
    • Julander, J., Mutton, N., (2011). The Complete Carpet Python: a comprehensive guide to the natural history, care, and breeding of the Morelia spilota complex. ECO herpetological publishing and distribution *
    • Book Chapters

    • Dagley, A., Julander, J., (2013). A mouse model of chikungunya virus with utility in antiviral studies: Antiviral Methods and Protocols. Springer
    • Julander, J., (2009). Antiviral treatment of flaviviruses: Antiviral Research: strategies in antiviral drug discovery. ASM Press

    * Has not been peer reviewed

    Publications - Fact Sheets

      * Has not been peer reviewed

      Publications - Curriculum

        * Has not been peer reviewed

        Publications - Journal Articles

          Academic Journal

        • Julander, J.G, Siddharthan, V., Evans, J., Taylor, R., Tolbert, K., Apuli, C., Stewart, J., Collins, P., Gebre, M., Neilson, S., Van Wettere, A., Lee, Y., Sheridan, W.P, Morrey, J.D, Babu, Y., (2017). Efficacy of the broad-spectrum antiviral compound BCX4430 against Zika virus in cell culture and in a mouse model. Antiviral Research (Antiviral Res), 137, 14-22. doi: 10.1016/j.antiviral.2016.11.003
        • Julander, J.G, Siddharthan, V., Evans, J., Taylor, R., Tolbert, K., Apuli, C., Stewart, J., Collins, P., Gebre, M., Neilson, S., Van Wettere, A., Lee, Y., Sheridan, W.P, Morrey, J.D, Babu, Y., (2017). Efficacy of the broad-spectrum antiviral compound BCX4430 against Zika virus in cell culture and in a mouse model. Antiviral Research (Antiviral Res), 137, 14-22. doi: 10.1016/j.antiviral.2016.11.003
        • Yun, S., Song, B., Frank, J.C, Julander, J.G, Polejaeva, I.A, Davies, C.J, White, K.L, Lee, Y., (2016). Complete genome sequences of three historically important, spatiotemporally distinct, and genetically divergent strains of Zika virus: MR-766, P6-740, and PRVABC-59. Genome Announcements (Genome Announc), 4:4, e00800-16. doi: 10.1128/genomeA.00800-16
        • Yun, S., Song, B., Frank, J.C, Julander, J.G, Polejaeva, I.A, Davies, C.J, White, K.L, Lee, Y., (2016). Complete genome sequences of three historically important, spatiotemporally distinct, and genetically divergent strains of Zika virus: MR-766, P6-740, and PRVABC-59. Genome Announcements (Genome Announc), 4:4, e00800-16. doi: 10.1128/genomeA.00800-16
        • Dagley, A., Ennis, J., Turner, J.D, Rood, K., Van Wettere, A., Gowen, B., Julander, J., (2014). Protection against Chikungunya virus induced arthralgia following prophylactic treatment with adenovirus vectored interferon (mDEF201). Antiviral Research, 108, 1-9. doi: 10.1016/j.antiviral.2014.05.004
        • Julander, J., Kesler, K., Van Wettere, A., Morrey, J.D, Smee, D., (2014). The use of plethysmography in determining the severity of lung pathology in a mouse model of minimally lethal influenza virus infection. Antiviral Research, 108, 10-13. doi: 10.1016/j.antiviral.2014.05.002
        • Chung, D.H, Jonsson, C.B, Tower, N.A, Chu, Y.K, Sahin, E., Golden, J.E, Noah, J.W, Shroeder, C.E, Sotsky, J.B, Sosa, M.I, Cramer, D.E, McKellip, S.N, Rasmussen, L., White, E.L, Schmaljohn, C.S, Julander, J., Smith, J.M, Filone, C.M, Connor, J.H, Sakurai, Y., Davey, R.A, (2014). Discovery of a novel compound with anti-venezuelan equine encephalitis virus activity that targets the nonstructural protein 2. PLoS Pathog., 10:6, e1004213. doi: 10.1371/journal.ppat.1004213
        • Julander, J., Thibodeaux, B., Morrey, J.D, Roehrig, J.T, Blair, C.D, (2014). Humanized monoclonal antibody 2C9-cIgG has enhanced efficacy for yellow fever prophylaxis and therapy in an immunocompetent animal model. Antiviral Research, 103, 32-38. doi: 10.1016/j.antiviral.2013.12.011
        • Wu, C.C, Crain, B., Yao, S., Sabet, M., Lao, F.S, Tawatao, R., Chan, M., Smee, D., Julander, J., Cottam, H.B, Guiney, D.G, Corr, M., Carson, D.A, Hayashi, T., (2014). Innate immune protection of infectious disease by pulmonary administration of phospholipid conjugated TLR7 ligands. Journal of Innate Immunity, 6:3, 315-324.
        • Wang, H., Siddharthan, V., Kessler, K.K, Hall, J.O, Motter, N.E, Julander, J., Morrey, J.D, (2013). Fatal neurological respiratory insufficiency is common among viral encephalitides. The Journal of Infectious Diseases, 208:4, 573-83.
        • Julander, J., Experimental therapies for yellow fever. Antiviral Research, 97:2, 169-179. doi: S0166-3542(12)00281-1. 10.1016/j.antiviral.2012.12.002
        • Nguyen, J.T, Smee, D., Barnard, D., Julander, J., Gross, M., De Jong, M., Went, G.T, , , (2012). Efficacy of combined therapy with amantadine, oseltamivir, and ribavirin in vivo against susceptible and amantadine-resistant influenza A viruses. PLoS ONE , 7(1): e31006, doi: 10.1371/journal.pone.0031006
        • Smee, D., Julander, J., Tarbet, B., Gross, M., Nguyen, J., (2012). Treatment of oseltamivir-resistant influenza A (H1N1) virus infections in mice with antiviral agents. Antiviral Research, 96, 13-20.
        • Julander, J., Hagloch, J., Latimer, S., Motter, N., Dagley, A., Barnard, D., Smee, D., Morrey, J.D, (2011). Use of plethysmography in assessing the efficacy of antivirals in a mouse model of pandemic influenza A virus. Antiviral Research, 92:2, 228-36.
        • Zasloff, M., Adams, A., Beckerman, B., Campbell, A., Han, Z., Luijten, E., Meza, I., Julander, J., Mishra, A., Qu, W., Taylor, J.M, Weaver, S.C, Wong, G.C, (2011). Squalamine as a broad-spectrum systemic antiviral agent with therapeutic potential. Proc Natl Acad Sci USA, 108:38, 15978-83.
        • Julander, J., Trent, D.W, Monath, T.P, (2011). Immune correlates of protection against yellow fever determined by passive immunization and challenge in the hamster model. Vaccine, 29:35, 6008-16.
        • Julander, J., Perry, S.T, Shresta, S., (2011). Important advancements in the field of anti-dengue virus research. Antivir. Chem. Chemother., 21:3, 105-16.
        • Gowen, B., Julander, J., London, N.R, Wong, M.H, Larson, D., Morrey, J.D, Li, D.Y, Bray, M., (2010). Assessing changes in vascular permeability in a hamster model of viral hemorrhagic fever. Virol. J., 7, 240.
        • Gowen, B., Julander, J., London, N.R, Wong, M.H, Larson, D., Morrey, J.D, Li, D.Y, Bray, M., (2010). Assessing changes in vascular permeability in a hamster model of viral hemorrhagic fever. Virol. J., 7:240, 1-13.
        • Lam, A.M, Murakami, E., Espiritu, C., Steuer, H.M, Niu, C., Keilman, M., Bao, H., Zennou, V., Bourne, N., Julander, J., Morrey, J.D, Smee, D., Frick, D.N, Heck, J.A, Wang, P., Nagarathnam, D., Ross, B.S, Sofia, M.J, Otto, M.J, Furman, P.A, (2010). PSI-7851, a pronucleotide of beta-D-2'-fluro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication. Antimicrob. Agents Chemother., 54:8, 3187-3196.
        • Julander, J., Jha, A.K, Choi, J.A, Jung, K.H, Smee, D., Morrey, J.D, Chu, C.K, (2010). Efficacy of 2'-C-methylcytidine against yellow fever virus in cell culture and in a hamster model. Antiviral Res., 86:3, 261-267.
        • Monath, T.P, Lee, C.K, Julander, J., Brown, A., Beasley, D.W, Watts, D.M, Hayman, E., Guertin, P., Makowiecki, J., Crowell, J., Levesque, P., Bowick, G.C, Morin, M., Fowler, E., Trent, D.W, (2010). Inactivated yellow fever 17D vaccine: development and nonclinical safety, immunogenicity and protective activity. Vaccine, 28:22, 3827-3840.
        • Julander, J., Smee, D., Morrey, J.D, Furuta, Y., (2009). Effect of T-705 treatment on western equine encephalitis in a mouse model. Antiviral Res., 82:3, 169-171.
        • Julander, J., (2009). Effect of T-705 treatment on western equine encephalitis in a mouse model. Antivirial Res., 82, 169-71.
        • Julander, J., (2009). T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections. Antivirial Res., 82, 95-102.
        • Furuta, Y., Takahashi, K., Shiraki, K., Sakamoto, K., Smee, D., Barnard, D., Gowen, B., Julander, J., Morrey, J.D, (2009). T-705 (favipiravir) and related compounds: novel broad-spectrum inhibitors of RNA viral infections. Antiviral Res, 82:3, 95-102.
        • Nair, V., Chi, G., Shu, Q., Julander, J., Smee, D., (2009). A heterocyclic molecule with significant activity against dengue virus. Bioorg. Med. Chem. Lett., 19:5, 1425-1427.
        • Nair, V., Chi, G., Shu, Q., Julander, J., Smee, D., (2009). A heterocyclic molecule with significant activity against dengue virus. Bioorg. Med. Chem. Lett., 19:5, 1425-1427.
        • Julander, J., Shafer, K., Smee, D., Morrey, J.D, Furuta, Y., (2009). Activity of T-705 in a hamster model of yellow fever virus infection in comparison with a chemically related compound T-1106. Antimicrob. Agents Chemother., 53:1, 202-209.
        • Julander, J., Shafer, K., Smee, D., Morrey, J.D, Furuta, Y., (2009). Activity of T-705 in a hamster model of yellow fever virus infection in comparison with a chemically related compound T-1106. Antimicrob. Agents Chemother., 53:1, 202-209.
        • Julander, J., Bowen, R.A, Rao, J.R, Day, C., Shafer, K., Smee, D., Morrey, J.D, Chu, C.K, (2008). Treatment of Venezuelan equine encephalitis virus infection with (-)-carbodine. Antiviral Res., 80:3, 309-315.
        • Julander, J., Bowen, R.A, Rao, J.R, Day, C., Shafer, K., Smee, D., Morrey, J.D, Chu, C.K, (2008). Treatment of Venezuelan equine encephalitis virus infection with (-)-carbodine. Antiviral Res., 80:3, 309-315.
        • Julander, J., Skirpstunas, R., Siddharthan, V., Shafer, K., Hoopes, J.D, Smee, D., Morrey, J.D, (2008). C3H/HeN mouse model for the evaluation of antiviral agents for the treatment of Venezuelan equine encephalitis virus infection. Antiviral Res., 78:3, 230-241.
        • Julander, J., Skirpstunas, R., Siddharthan, V., Shafer, K., Hoopes, J.D, Smee, D., Morrey, J.D, (2008). C3H/HeN mouse model for the evaluation of antiviral agents for the treatment of Venezuelan equine encephalitis virus infection. Antiviral Res., 78:3, 230-241.
        • Selvam, P., Vijayalakshimi, P., Smee, D., Gowen, B., Julander, J., Day, C.W, Barnard, D., (2007). Novel 3-sulphonamido-quinazolin-4(3H)-one derivatives: microwave-assisted synthesis and evaluation of antiviral activities against respiratory and biodefense viruses.. Antiviral Chemistry and Chemotherapy/International Medical Press, 18:5, 301-5.
        • Morrey, J.D, Siddharthan, V., Olsen, A.L, Wang, H., Julander, J., Hall, J.O, Li, H., Nordstrom, J.L, Koenig, S., Johnson, S., Diamond, M.S, (2007). Defining limits of treatment with humanized neutralizing monoclonal antibody for West Nile virus neurological infection in a hamster model.. Antimicrob. Agents Chemother., 51 (7), 2396-402.
        • Julander, J., Judge, J.W, Olsen, A.L, Rosenberg, B., Shafer, K., Sidwell, R.W, (2007). Prophylactic treatment with recombinant Eimeria protein, alone or in combination with an agonist cocktail, protects mice from Banzi virus infection.. Antiviral Research, 75(1), 14-19.
        • Julander, J., Furuta, Y., Shafer, K., Sidwell, R.W, (2007). Activity of T-1106 in a hamster model of yellow fever virus infection.. Antimicrob. Agents Chemother., 51(6), 1962-6.
        • Julander, J., Siddharthan, V., Blatt, L.M, Shafer, K., Sidwell, R.W, Morrey, J.D, (2007). Effect of exogenous interferon and an interferon inducer on western equine encephalitis virus disease in a hamster model. Virology, 360:2, 454-460.
        • Julander, J., Morrey, J.D, Blatt, L.M, Shafer, K., Sidwell, R.W, (2007). Comparison of the inhibitory effects of interferon alfacon-1 and ribavirin on yellow fever virus infection in a hamster model. Antiviral Res., 73:2, 140-146.
        • Stuyver, L.J, McBrayer, T.R, Tharnish, P.M, Clark, J., Hollecker, L., Lostia, S., Nachman, T., Grier, J., Bennett, M.A, Xie, M.Y, Schinazi, R.F, Morrey, J.D, Julander, J., Furman, P.A, Otto, M.J, (2006). Inhibition of hepatitis C replicon RNA synthesis by beta-D-2'-deoxy-2'fluoro-2'-C-methylcytidine: a specific inhibitor of hepatitis C virus replication. Antiv. Chem. Chemother., 17:2, 79-87.
        • Julander, J., Winger, Q.A, Rickords, L.F, Shi, P.Y, Tilgner, M., Binduga-Gajewska, I., Sidwell, R.W, Morrey, J.D, (2006). West Nile virus infection of the placenta.. Virology, 347:1, 175-182.
        • Day, C.W, Smee, D., Julander, J., Yamshchikov, V.F, Sidwell, R.W, Morrey, J.D, (2005). Error-prone replication of West Nile virus caused by ribavirin.. Antiviral Res., 67:1, 38-45.
        • Julander, J., Winger, Q.A, Olsen, A.L, Day, C.W, Sidwell, R.W, Morrey, J.D, (2005). Treatment of West Nile virus-infected mice with reactive immunoglobulin reduces fetal titers and increased dam survival. Antiviral Res., 65:2, 79-85.
        • Morrey, J.D, Day, C.W, Julander, J., Olsen, A.L, Sidwell, R.W, Cheney, C.D, Blatt, L.M, (2004). Modeling hamsters for evaluating West Nile virus therapies.. Antiviral Res., 63:1, 41-50.
        • Iyer, R.P, Roland, A., Jin, Y., Mounir, S., Korba, B., Julander, J., Morrey, J.D, (2004). Anti-hepatitis B virus activity of ORI-9020, a novel phosphorothioate dinucleotide, in a transgenic mouse model.. Antimicrob Agents Chemother, 48:6, 2318-2320.
        • Morrey, J.D, Day, C.W, Julander, J., Blatt, L.M, Smee, D., Sidwell, R.W, (2004). Effect of interferon-alpha and interferon-inducers on West Nile virus in mouse and hamster animal models.. Antivir Chem Chemother, 15:2, 101-109.
        • Julander, J., Colonno, R.J, Sidwell, R.W, Morrey, J.D, (2003). Characterization of antiviral activity of entecavir in transgenic mice expressing hepatitis B virus.. Antiviral Res, 59:3, 155-161.
        • Julander, J., Sidwell, R.W, Morrey, J.D, (2002). Characterizing antiviral activity of adefovir dipivoxil in transgenic mice expressing hepatitis B virus. Antiviral Res., 55:1, 27-40.
        • Professional Journal

        • Richner, J.M, Himansu, S., Butler, S., Dowd, K.A, Salazar, V., Fox, J.M, Julander, J., Tang, W.W, Shresta, S., Pierson, T.C, Ciaramella, G., Diamond, M.S, (2017). A modified mRNA vaccine platform protects against Zika virus pathogenesis and minimizes antibody-dependent enhancement of Dengue virus infection. Cell, 168:6, 1114-1125.e10. doi: 10.1016/j.cell.2017.02.017
        • Guo, F., Wu, S., Julander, J., Ma, J., Zhang, X., Kulp, J., Cuconati, A., Block, T.M, Du, Y., Guo, J., Chang, J., (2016). A novel benzodiazepine compound inhibits yellow fever virus infection by specifically targeting NS4B protein. Journal of VirologyJVI.01253-16
        • Julander, J., (2016). Animal models of yellow fever and their application in clinical research. Curr. Opin. Virol., 18, 64-9. doi: 10.1016/j.coviro.2016.03.010.
        • Taylor, R., Kotian, P., Warren, T., Bavari, S., Julander, J., Dobo, S., Rose, A., El-Kattan, Y., Taubenheim, B., Babu, Y., Sheridan, W.P, (2016). BCX4430 - a broad-spectrum antiviral adenosine nucleoside analog under development for the treatment of Ebola virus disease. J. Infect. Public Health, 9:3, 220-6. doi: 10.1016/j.jiph.2016.04.002
        • Julander, J., Bantia, S., Taubenheim, B.R, Minning, D.M, Kotian, P., Morrey, J.D, Smee, D., Sheridan, W.P, Babu, Y.S, (2014). BCX4430, a novel nucleoside analog, effectively treats yellow fever in a hamster model. Antimicrobial Agents and Chemotherapy, 58:11, 6607-6614.
        • Wang, H., Siddharthan, V., Kesler, K., Hall, J.O, Motter, N.E, Julander, J., Morrey, J.D, (2013). Autonomic Deficit not the Cause of Death in West Nile Virus Neurological Disease. J Infect Dis, 204:4, 573-583.
        • Wand, H., Siddharthan, V., Kesler, K., Hall, J.O, Motter, N.E, Julander, J., Morrey, J.D, (2013). Autonomic Deficit not the Cause of Death in West Nile Virus Neurological Disease. J Infect Dis, 204:4, 573-583.
        • Julander, J., Ennis, J., Turner, J., Morrey, J.D, (2011). Treatment of yellow fever virus with an adenovirus-vectored interferon, DEF201, in a hamster model. Antimicrob. Agents Chemother., 55:5, 2067-73.

        * Has not been peer reviewed

        Publications - Literary Journal

          * Has not been peer reviewed

          Publications - MultiMedia

            * Has not been peer reviewed

            Publications - Technical Reports

              Research Reports

            • Smee, D., Barnard, D., Morrey, J.D, Gowen, B., Julander, J., (2009). Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Smee, D., Barnard, D., Morrey, J.D, Gowen, B., Julander, J., (2009). Semi-Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Smee, D., Barnard, D., Morrey, J.D, Gowen, B., Julander, J., (2008). Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Smee, D., Barnard, D., Morrey, J.D, Gowen, B., Julander, J., (2008). Semi-Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Smee, D., Barnard, D., Morrey, J.D, Gowen, B., Julander, J., (2007). Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Smee, D., Barnard, D., Morrey, J.D, Gowen, B., Julander, J., (2007). Semi-Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., Julander, J., (2006). Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., Julander, J., (2006). Semi Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .

            * Has not been peer reviewed

            Publications - Translations & Transcripts

              Publications - Other

                * Has not been peer reviewed

                Extension

                Evaluation of Antiviral Agents in Animal Models of Viral Disease, - Ongoing
                HDTRA1-08-C-0003, - Ongoing
                Influenza work, - Ongoing
                Pharmaceutical, - Ongoing
                Screening of antiviral compounds in cell culture, - Ongoing

                Graduate Students Mentored

                Chad Clancey, Animal, Dairy and Veterinary Sciences, August 2015
                Makda Gebre, Animal, Dairy and Veterinary Sciences, August 2015
                Ashley Dagley, Animal, Dairy and Veterinary Sciences, January 2009 - November 2015