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Dale Barnard

Profile Picture

Animal, Dairy and Veterinary Sciences

Antiviral Chemotherapy

Research Professor

Educational Background

Other, Antiviral Chemotherapy, (Chemotherapy of Viruses), Utah State University, 1988
PhD, Microbiology, (Virology), Brigham Young University, 1987
Analysis of the Virion of Aleutian Disease Virus of Mink
MS, Microbiology, (Biochemistry), Idaho State University, 1979
A Characterization of the Interaction between Salmonella typhimurium MR10 and HeLa Cells
BS, Microbiology, Weber State College, 1977





Contact Information

Go toOffice Location: VSB 301
DialPhone: 435-797-2696
SendEmail: dale.barnard@usu.edu

Awards

James LeGrande Shuope Achievement Award, 2015

ADVS

Outstanding Service-ASM Online Minority Mentor, 2010

American society for Microbiology

Top Reviewer, 2009

Antiviral Research

USU International Student Council Professor of the Year, 2000

USU International Student Council

Mortar Board Top Professor, 2000

USU Mortar Board

    Publications - Books & Book Chapters

      Book Chapters

    • Smee, D., Barnard, D., (2013). Methods for evaluation of antiviral efficacy against influenza virus infections in animal models. Methods in Molecular Biology
    • Barnard, D., (2010). Human parainfluenza virus type 3 (HPIV-3): construction and rescue of an infectious, recombinant virus expressing the enhanced green fluorescent protein (EGFP).. Current protocols in microbiology/John Wiley
    • Sidwell, R.W, Smee, D.F, Barnard, D., (2006). Development of antiviral drugs against avian (H5N1) influenza virus: Recent Developments on the Avian Influenza (H5N1) Crisis. Recent Developments on the Avian Influenza (H5N1) Crisis/Transworld Research Network
    • Mangel, W.F, Toledo, D.L, Brown, M.T, Ding, J., Sweet, R.M, Barnard, D., McGrath, W.J, (2000). Adenovirus proteinase-antiviral target for triple-combination therapy on a single enzyme: Potential inhibitor binding sites: Proteases as Targets for Therapy: Handbook of Experimental Pharmacology. Springer-Verlag

    * Has not been peer reviewed

    Publications - Fact Sheets

      * Has not been peer reviewed

      Publications - Curriculum

        * Has not been peer reviewed

        Publications - Journal Articles

          Academic Journal

        • Vollmer, A.H, Gebre, M.S, Barnard, D.L, (2016). Serum amyloid A (SAA) is an early biomarker of influenza virus disease in BALB/c, C57BL/2, Swiss-Webster, and DBA.2 mice. Antiviral Research, 133, 196-207. doi: 10.1016/j.antiviral.2016.08.011
        • Tarbet, B., Vollmer, A.H, Hurst, B.L, Barnard, D., Furuta, Y., Smee, D., (2014). In vitro activity of favipiravir and neuraminidase inhibitor combinations against oseltamivir-sensitive and oseltamivir-resistant pandemic influenza A (H1N1) virus. Archives of Virology, 159:6, 1279-1291.
        • Furuta, Y., Gowen, B., Takahashi, K., Shiraki, K., Smee, D., Barnard, D., (2013). Favipiravir (T-705), a novel viral RNA polymerase inhibitor. Antiviral Research, 100:2, 446-454.
        • Smee, D., Tarbet, B., Furuta, Y., Morrey, J.D, Barnard, D., (2013). Synergistic combinations of favipiravir and oseltamivir against wild-type pandemic and oseltamivir-resistant influenza A virus infections in mice. Antiviral Research, 8:11, 1085-1094.
        • Roth, J.P, Li, J.K, Morrey, J.D, Barnard, D.L, Vollmer, A.H, (2013). Deletion of the D domain of the human parainfluenza virus type 3 (HPIV3) PD protein results in decreased viral RNA synthesis and beta interferon (IFN-b) expression. Virus Genes/Springer, 47, 10. doi: 10.1007/s11262-013-0919-x
        • Kesel, A.J, Weiss, H., Shoenleber, A., Day, C., Barnard, D., Detorio, M.A, Schinazi, R.F, , , , (2012). Antiviral agents derived from novel 1-adamantyl singlet nitrenes. Antiviral Chemistry & Chemotherapy/International Medical Press, online. doi: 10.3851/IMP2485
        • Nguyen, J.T, Smee, D., Barnard, D., Julander, J., Gross, M., De Jong, M., Went, G.T, , , (2012). Efficacy of combined therapy with amantadine, oseltamivir, and ribavirin in vivo against susceptible and amantadine-resistant influenza A viruses. PLoS ONE , 7(1): e31006, doi: 10.1371/journal.pone.0031006
        • Kumaki, Y., Ennis, J., Rahbar, R., Turner, J.D, Wandersee, M.K, Smith, A.J, Bailey, K.W, Vest, Z.G, Madsen, J.R, Li, J.K, Barnard, D., (2011). Single-dose intranasal administration with mDEF201 (adenovirus vectored mouse interferon-alpha) confers protection from mortality in a lethal SARS-CoV BALB/c mouse model. . Antiviral Research, 89:1, 75-82.
        • Kumaki, Y., Wandersee, M.K, Smith, A.J, Zhou, Y.J, simmons, G., Nelson, N.M, Bailey, K.W, Vest, Z.G, Li, J.K, Chan, P.K, Smee, D.F, Barnard, D., (2011). Inhibition of severe acute respiratory syndrome coronavirus replication in a lethal SARS-CoV BALB/c mouse model by stinging nettle lectin, Urtica dioica agglutinin. Antiviral Research/Elsevier
        • Kumaki, Y., Craig, D., Morrey, J.D, Smee, D., Barnard, D., (2011). In vitro and in vivo efficacy of fluorodeoxycytidine analogs against highly pathogenic avian influenza H5N1, seasonal, and pandemic H1N1 virus infections. . Antiviral Research/Elsevier, 92:2, 329-340.
        • Julander, J., Hagloch, J., Latimer, S., Motter, N., Dagley, A., Barnard, D., Smee, D., Morrey, J.D, (2011). Use of plethysmography in assessing the efficacy of antivirals in a mouse model of pandemic influenza A virus. Antiviral Research, 92:2, 228-36.
        • Liu, Y.V, Massare, M.J, Barnard, D., Kort, T., Nathan, M., Wang, L., (2011). Chimeric severe acute respiratory syndrome coronavirus (SARS-CoV) S glycoprotein and influenza matrix 1 efficiently form virus-like particles (VLPs) that protect mice against challenge with SARS-CoV.. Vaccine/Elsevier, 29:38, 6606-6613.
        • Barnard, D., Kumaki, Y., (2011). Recent developments in anti-severe acute respiratory syndrome coronavirus chemotherapy. . Future Virology, 6:5, 615-631.
        • Yang, C.W, Lee, Y.Z, Kang, I.J, Barnard, D., Jan, J.T, Lin, D., Huang, C.W, Yeh, T.K, Chao, Y.S, Lee, S.J, (2010). Identification of phenanthroindolizines and phenanthroquinolizidines as novel potent anti-coronaviral agents for porcine enteropathogenic coronavirus transmissible gastroenteritis virus and human severe acute respiratory syndrome coronavirus.. Antiviral Research/Elsevier, 88, 160-168.
        • Rao, J.R, Jha, A.K, Rawal, R.K, Sharon, A., Day, C.W, Barnard, D., Smee, D., Chu, C.K, (2010). (-)-Carbodine: enantiomeric synthesis and in vitro antiviral activity against various strains of influenza virus including H5N1 (avian influenza) and novel 2009 N1N1 (swine flu) . Bioorg. Med. Chem. Lett. , 20:8, 2601-2604.
        • O'Keefe, B.R, Giomarelli, G., Barnard, D., Shenoy, S.R, Chan, P.K, McMahon, J.B, Palmer, K.E, Barnett, B.W, Meyerholz,, D.K, Wohlford-Lenane, C.L, McCray, Jr., P.B, (2010). Broad Spectrum in vitro Activity and in vivo Efficacy of the Antiviral Protein Griffithsin Against Emerging Viruses of the Family Coronaviridae.. Journal of Virology/ASM Press, 84:5, 2511-2521.
        • Silvers, L., Barnard, D., Knowlton, F., Inglis, B., Labudovic, A., Holland, M.K, Janssens, P.K, van Leeuwen, B.H, Kerr, P.J, (2010). Host-specificity of myxoma virus: Pathogenesis of South American and North American strains of myxoma virus in two North American lagomorph species.. Vet Microbiol., 141:3-4, 289-300.
        • 76. London, N.r, Zhu, W., Bozza, F.A, Smith, M.C, Greif, D.M, Sorensen, L.K, Chen, L., Kaminoh, Y., Chan, A.C, Passi, S.F, Day, C.W, Barnard, D., Zimmerman, G.A, Krasnow, M.A, Li, D.Y, (2010). Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and influenza.. Science translational medicine/American Association for the Advancement of Science , 2:23, 23ra19.
        • Kumaki, Y., Day, C.W, Bailey, K.W, Wandersee, M.K, Wong, M., Madsen, J.R, Madsen, J.S, Nelson, N.M, Hoopes, J.D, Woolcott, J.D, McLean, T.Z, Blatt, L.M, Salazar, A.M, Smee, D., Barnard, D., (2010). Induction of interferon-gamma-inducible protein 10 by SARS-CoV infection, interferon alfacon 1 and interferon inducer in human bronchial epithelial Calu-3 cells and BALB/c mice. Antiviral chemistry & chemotherapy/International Medical Press, 20:4, 169-177.
        • Day, C.W, Baric, R., Cai, S.X, Freeman, M., Kumaki, Y., Morrey, J.D, Smee, D., Barnard, D., (2009). A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo . Virology, 395:2, 210-222.
        • Wiley, J.A, Richert, L.E, Swain, S.D, Harmsen, A., Barnard, D., Randall, T.D, Jutila, M., Douglas, T., Broomell, C., Young, M., Harmsen, A., (2009). Inducible Bronchus-Associated Lymphoid Tissue Elicited by a Protein Cage Nanoparticle Enhances Protection in Mice against Diverse Respiratory Viruses.. PLoS ONE/Public Library of Science, 4:9, e7142.
        • Furuta, Y., Takahashi, K., Shiraki, K., Sakamoto, K., Smee, D., Barnard, D., Gowen, B., Julander, J., Morrey, J.D, (2009). T-705 (favipiravir) and related compounds: novel broad-spectrum inhibitors of RNA viral infections. Antiviral Res, 82:3, 95-102.
        • Barnard, D., (2009). Animal models for the study of influenza pathogenesis and therapy. Antiviral Research/Elsevier, 82:2, A110-A122.
        • Roth, J.P, Li, J.K, Smee, D., Morrey, J.D, Barnard, D., (2009). A recombinant, infectious human parainfluenza virus type 3 expressing the enhanced green fluorescent protein for use in high-throughput antiviral assays. Antiviral Res., 82:1, 12-21.
        • Smee, D.F, Humphreys, D.E, Hurst, B.L, Barnard, D., (2008). Antiviral activities and phosphorylation of 5-halo-2'-deoxyuridines and N-methanocarbathymidine in cells infected with vaccinia virus.. Antiviral Chemistry & Chemotherapy/Blackwell Scientific Publications, 19:1, 15-24.
        • Barnard, D., Day, C.W, Bailey, K., Heiner, M., Montgomery, R., Lauridsen, L., Jung, K.-, Chan, P.K, Li, J.K, Sidwell, R.W, (2008). Is the anti-psychotic, 10-(3-(Dimethylamino)propyl)phenothiazine (Promazine), a dangerous drug with which to treat SARS infections? Efficacy of Promazine on SARS-CoV replication in a mouse model. Antiviral Research, 79:2, 110-113.
        • Kumaki, Y., Day, C.W, Wandersee, M.K, Schow, B.P, Madsen, J.S, Grant, D., Roth, J.P, Smee, D., Blatt, L.M, Barnard, D., (2008). Interferon alfacon 1 inhibits SARS-CoV infection in human bronchial epithelial Calu-3 cells. Biochem. Biophys. Res. Commun., 371:1, 110-113.
        • Subramanian, G.M, Moore, P.A, Gowen, B., Olsen, A.L, Barnard, D., Paragas, J., Hogan, R.J, Sidwell, R.W, (2008). Potent in vitro activity of the albumin fusion type 1 interferons (albumin-interferon-alpha and albumin-interferon-beta) against RNA viral agents of bioterrorism and the severe acute respiratory syndrome (SARS) virus. Chemotherapy, 54:3, 176-180.
        • Selvam, P., Vijayalakshimi, P., Smee, D., Gowen, B., Julander, J., Day, C.W, Barnard, D., (2007). Novel 3-sulphonamido-quinazolin-4(3H)-one derivatives: microwave-assisted synthesis and evaluation of antiviral activities against respiratory and biodefense viruses.. Antiviral Chemistry and Chemotherapy/International Medical Press, 18:5, 301-5.
        • Hu, M.C, Jones, T., Kenney, R.T, Barnard, D., Burt, D.S, Lowell, G.H, (2007). Intranasal Protollin-formulated recombinant SARS S-protein elicits respiratory and serum neutralizing antibodies and protection in mice. Vaccine/Elsevier, 25:34, 6334-6340.
        • Barnard, D., Wong, M.-, Bailey, K., Day, C.W, Sidwell, R.W, Hickok, S.S, Hall, T.J, (2007). Effect of Oral Gavage Treatment with ZnAL42 and Other Metallo-ion formulations on Influenza A H5N1 and H1N1 Virus Infections in Mice. Antiviral Chemistry and Chemotherapy/International Medical Press, 18:3, 125-132.
        • Borkow, G., Sidwell, R.W, Smee, D.F, Barnard, D., Morrey, J.D, Lara-Villegas, H.H, Shemer-Avni, Y., Gabbay, J., (2007). Neutralizing viruses in suspensions by copper oxide 1 based filters. Antimicrobial Agents and Chemotherapy/ASM Press, 51:7, 2605-2607.
        • Sidwell, R.W, Barnard, D., Day, C.W, Smee, D.F, Bailey, K.W, Wong, M.-, Morrey, J.D, Furuta, Y., (2007). Efficacy of orally administered T-705 on lethal avian influenza A (H5N1) virus infections in mice. Antimicrobial Agents and Chemotherapy/ASM Press, 51:3, 845-851.
        • Barnard, D., Day, C.W, Bailey, K., Heiner, M., Montgomery, R., Lauridsen, L., Chan, P.K, Sidwell, R.W, (2006). Evaluation of immune modulators, interferons and known in vitro SARS-CoV inhibitors for inhibition of SARS-CoV replication in BALB/c mice. Antiviral Chemistry and Chemotherapy/International Medical Press, 17:5, 275-284.
        • Barnard, D., Day, C.W, Bailey, K., Heiner, M., Montgomery, R., Lauridsen, L., Winslow, S., Hoopes, J., Li, J.K, Lee, J., Carson, D.A, Cottam, H.B, Sidwell, R.W, (2006). Enhancement of the infectivity of SARS-CoV in BALB/c mice by IMP dehydrogenase inhibitors, including ribavirin. Antiviral Research/Elsevier, 71:1, 53-63.
        • Sidwell, R.W, Barnard, D., (2006). Respiratory Syncytial Virus Infections: Recent Prospects for Control. . Antiviral Research/Elsevier, 71:2-3, 379-390.
        • Chu, C.K, Gadthula, S., Chen, X., Choo, H., Olgen, S., Sidwell, R.W, Barnard, D., (2006). Antiviral activity of nucleoside analogs against SARS-Coronavirus. Antiviral Chemistry and Chemotherapy/International Medical Press, 17:5, 285-289.
        • Barnard, D., (2006). Respiratory Syncytial Virus Infections: Recent Prospects for Control. Antiviral Res, 71, 379-390.
        • Barnard, D., (2006). Current status of anti-picornavirus therapies. Current Pharmaceutical Design/Bentham Science Publishers, 12:11, 1379-1390.
        • Barnard, D., (2006). Efficacy of Orally Administered T-705 on Lethal Avian Influenza A (H5N1) Virus Infections in Mice. Antimicrobial Agents and Chemotherapy/ASM Press, 51:3, 845-851.
        • Cho, J.H, Barnard, D., Sidwell, R.W, Kern, E.R, Chu, C.K, (2006). Synthesis of cyclopentenyl carbocyclic nucleosides as potential antiviral agents against orthopoxviruses and SARS. . Journal of Medicinal Chemistry/American Chemical Society, 49:3, 1140-1148.
        • Sidwell, R.W, Bailey, K.W, Wong, M.-, Barnard, D., Smee, D.F, (2005). In vitro and in vivo influenza virus-inhibitory effects of viramidine. Antiviral Research/Elsevier, 68:1, 10-17.
        • Gowen, B.B, Barnard, D., Smee, D.F, Wong, M.-, Pace, A.M, Jung, K.-, Winslow, S.G, Bailey, K.W, Blatt, L.M, Sidwell, R.W, (2005). Interferon alfacon-1 protects hamsters from lethal pichinde virus infection.. Antimicrobial Agents and Chemotherapy/ASM Press, 49:6, 2378-2386.
        • Barnard, D., (2004). Inhibitors of measles virus. Antiviral chemistry & chemotherapy/International Medical Press, 15:3, 111-119.
        • Barnard, D., Hubbard, V.D, Smee, D.F, Sidwell, R.W, Watson, K.G, Tucker, S.P, Reece, P.A, (2004). In vitro activity of expanded-spectrum pyridazinyl oxime ethers related to pirodavir: novel capsid-binding inhibitors with potent anti-picornavirus activity. Antimicrobial Agents and Chemotherapy/ASM Press, 48:5, 1766-1772.
        • Barnard, D., Hubbard, V.D, Burton, J., Smee, D.F, Morrey, J.D, Otto, M.J, Sidwell, R.W, (2004). Inhibition severe acute respiratory syndrome-associated coronavirus (SARSCoV) by clapain inhibitors and B-D-N4-hydroxycytidine. Antiviral Chemistry & Chemotherapy/International Medical Press, 15:1, 15-22.
        • Watson, K.G, Brown, R.N, Cameron, R., Chalmers, D.K, Hamilton, S., Jin, B., Krippner, G.Y, McConnell, D.B, Reece, P.A, Ryan, J., Stanislawski, P.C, Tucker, S.P, Wu, W.Y, Barnard, D., Sidwell, R.W, (2003). An orally bioavailable oxime ether capsid binder with potent activity against human rhinovirus. Journal of Medicinal Chemistry/American Chemical Society, 46:15, 3181-3184.
        • Zhang, N., Chen, H.M, Sood, R., Kalicharran, K., Fattom , A.I, Naso, R.B, Barnard, D., Sidwell, R.W, Hosmane, R.S, (2002). In vitro inhibition of the measles virus by novel ring-expanded ('fat') nucleoside analogues containing the imidozo[4,5-e]diazepine ring system. Bioorganic and Medicinal Chemistry Letters/Elsevier, 12:23, 3391-3394.
        • Barnard, D., (2002). Viramidine. Current Opinion in Investigational Drugs/Thomson Reuters (Scientific) Ltd, 3:11, 1585-1589.
        • Smee, D.F, Morrison, A.C, Barnard, D., Sidwell, R.W, (2002). Comparison of colorimetric, fluorometric, and visual methods of determining anti-influenza (H1N1 and H3N2) virus activities and toxicities of compounds. Journal of Virological Methods/Elsevier, 106:1, 71-79.
        • Barnard, D., (2002). Interferon-alpha. Current Opinion in Investigational Drugs/Thomson Reuters (Scientific) Ltd, 3:5, 693-697.
        • Barnard, D., Xu, Z.Q, Stowell, V.D, Yuan, H., Smee, D.F, Samy, R., Sidwell, R.W, Nielsen, M.K, Sun, L., Cao, H., Li, A., Quint, C., Deignan, J., Crabb, J., Flavin, M.T, (2002). Coumarins and pyranocoumarins, potential novel pharmacophores for inhibition of measles virus replication. Antiviral Chemistry and Chemotherapy/International Medical Press, 13:1, 39-59.
        • Sidwell, R.W, Wong, M.-, Bailey, K.W, Barnard, D., Jackson, M.K, Smee, D.F, (2001). Utilization of alpha-1-acid glycoprotein levels in the serum as a parameter for in vivo assay of influenza virus inhibitors. Antiviral Chemistry and Chemotherapy/International Medical Press, 12:6, 359-365.
        • Sidwell, R.W, Smee, D.F, Huffman, J.H, Barnard, D., Morrey, J.D, Bailey, K.W, Feng, W.C, Babu, Y.S, Bush, K., (2001). Influence of virus strain, challenge dose, and time of therapy initiation on the in vivo influenza inhibitory effects of RWJ-270201.. Antiviral Research/Elsevier, 51:3, 179-187.
        • Mangel, W.F, McGrath, W.J, Brown , M.T, Baniecki , M.L, Barnard, D., Pang, Y.P, (2001). A new form of antiviral combination therapy predicted to prevent resistance from arising, and amodel system to test it. Current Medicinal Chemistry/Bentham Science Publishers, 8:8, 933-939.
        • Barnard, D., Stowell, V.D, Seley, K.L, Hegde, V.R, Das, S.R, Rajappan, V.P, Schneller , S.W, Smee, D.F, Sidwell, R.W, (2001). Inhibition of measles virus replication by 5'-Nor carbocyclic nucleoside analogs. Antiviral Chemistry & Chemotherapy/International Medical Press, 12:4, 221-230.
        • Barnard, D., (2001). Genvir. Current Opin Investig Drugs, 2:5, 622-623.
        • Mangel, W.F, Brown, M.T, Baniecki , M.L, Barnard, D., McGrath, W.J, (2001). Prevention of viral drug resistance by novel combination therapy. Current Opinion in Investigational Drugs/Thomson Reuters (Scientific) Ltd, 2:5, 613-616.
        • Barnard, D., , , , , , (2001). Cyclopentane neuraminidase inhibitors with potent in vitro anti-influenza virus activities. . Antimicrobial Agents and Chemotherapy/ASM Press, 45:3, 743-748.
        • Sidwell, R.W, Smee, D.F, Huffman, J.H, Barnard, D., Bailey, K.W, Morrey, J.D, Babu, Y.S, (2001). In vivo influenza virus-inhibitory effects of the cyclopentane neuraminidase inhibitor RJW-270201.. Antimicrobial Agents and Chemotherapy/ASM Press, 45:3, 749-757.
        • Barnard, D., (2000). Technology evaluation: Sch-58500, Canji.. Current Opinion in Molecular Therapeutics/Thomson Reuters (Scientific) Ltd, 2:5, 586-592.
        • Barnard, D., (2000). Pegasys. Current Opinion in Investigational Drugs/Thomson Reuters (Scientific) Ltd, 2:11, 1530-1538.
        • Barnard, D., (2000). RWJ-270201. Current Opinion in Investigational Drugs/Thomson Reuters (Scientific) Ltd, 1:4, 421-424.
        • Barnard, D., (1999). RSV vaccine (subunit) Wyeth-Lederle vaccines.. Current Opinion in Anti-Infective Investigational Drugs/Current Drugs Ltd, 1, 627-631.
        • Barnard, D., (1999). 2-5A-antisense inhibition of respiratory syncytial virus replication: Effects of oligonucleotide structure modifications and RNA target site selection. Antiviral Research/Elsevier, 41:3, 119-134.
        • Barnard, D., (1999). Antiviral activities of biflavonoids. Planta Medica/George Thieme, 65:2, 120-125.
        • Player, M.R, Barnard, D., Torrence, P.F, (1998). Potent inhibition of respiratory syncytial virus replication using a 2-5A-antisense chimera targeted to signals within the virus genomic RNA. Proceedings of the National Academy of Sciences of the United States of America/National Academy of Sciences, 95:15, 8874-8879.
        • Sidwell, R.W, Huffman, J.H, Barnard, D., Bailey, K.W, Wong, M.-, Morrison, A., Syndergaard, T., Kim, C.U, (1998). Inhibition of influenza virus infections in mice by GS4104, an orally effective influenza virus neuraminidase inhibitor. Antiviral Research/Elsevier, 37:2, 107-120.
        • Barnard, D., Bischofberger, N., Kim, C., Huffman, J.H, Sidwell, R.W, Dougherty, J.P, Lew, W., Williams, M.A, Yang, W., (1997). Acyclic phosphonomethylether nuculeoside inhibitors of respiratory viruses. Antiviral Chemistry & Chemotherapy/International Medical Press, 8:3, 223-233.
        • Huffman, J.H, Sidwell, R.W, Barnard, D., Morrison, A., Otto, M.I, Hill, C.L, Schinazi, R.F, (1997). In vitro influenza virus-inhibitory effects of a series of germanium- or silicon-centered polyoxometalates.. Antiviral chemistry & chemotherapy/International Medical Press, 8:2, 75-83.
        • Barnard, D., Hill, C.L, Gage, T., Matheson, J.E, Huffman, J.H, Sidwell, R.W, Otto, M.I, Schinazi, R.F, (1997). Potent inhibition of respiratory syncytial virus by polyoxometalates of several structural classes. Antiviral Res, 34:1, 27-37.
        • Jackson, M.K, Ellis, L.C, Morrey, J.D, Li, Z.-, Barnard, D., (1996). Progression of Aleutian disease in natural and experimentally induced infections of mink. American Journal of Veterinary Research/American Veterinary Medical Association, 57:12, 1753-1758.
        • Barnard, D., Fairbairn,, D.W, O'Neill, K.L, Gage, T.L, Sidwell, R.W, (1995). Anti-human cytomegalovirus activity and toxicity of sulfonated anthraquinones and anthraquinone derivatives.. Antiviral Research/Elsevier, 28:4, 317-329.
        • Sidwell, R.W, Huffman, J.H, Barnard, D., Smee, D.F, Warren, R.P, Chirigos, M.A, Kende, M., Huggins, J.W, (1994). Antiviral and immunomodulating inhibitors of experimentally-induced Punt Toro virus infections. Antiviral Research/Elsevier, 25:2, 105-122.
        • Ubillas, R., Jolad, S.D, Bruening, R.C, Kernan, M.R, King, S.R, Sesin, D.F, Barrett, M., Stoddart, C.A, Flaster, T., Kuo, J., Ayala,, F., Meza, E., Castanel, M., McMeekin, D., Rozhon, E., Tempesta, M.S, Barnard, D., Smee, D.F, Sidwell, R.W, Soike, K., Brazier, A., Safrin, S., Orlando, R., Kenney, P.T, Berova, N., Nakinishi, K., (1994). SP-303, an antiviral oligomeric protanthocyanidin from the latex of Croton lechleri (Sangre de Drago). Phytomedicine, 1, 77-106.
        • Jackson, M.K, Ellis, L.C, Morrey, J.D, Barnard, D., (1993). Detection of Aleutian disease virus in natural infections.. Faseb Journal/ederation of American Societies for Experimental Biology, 7, A502.
        • Barnard, D., Huffman, J.H, Sidwell, R.W, Reist, E.J, (1993). Selective inhibition of cytomegaloviruses by 9-(3'-ethylphosphono-1'-hydroxymethyl-1'-propyloxy-methyl)guanine.. Antiviral Research/Elsevier, 22:1, 77-89.
        • Barnard, D., Smee, D.F, Huffman, J.H, Meyerson, L.R, Sidwell, R.W, (1993). Anti-herpesvirus activity and mode of action of SP-303, a novel plant flavenoid. Chemotherapy/Karger, 39:3, 212-217.
        • Barnard, D., Huffman, J.H, Meyerson, R.R, Sidwell, R.W, (1993). Mode of inhibition of respiratory syncytial virus by a plant flavonoid, SP-303. Chemotherapy/Karger, 39:3, 212-217.
        • Smee, D.F, Morris, J.L, Barnard, D., Van Aerschot, A., (1992). Selective inhibition of arthropod-borne and arenaviruses in vitro by 3'-fluoro-3'-deoxyadenosine. Antiviral Research/Elsevier, 18:2, 151-162.
        • Barnard, D., Huffman, J.H, Morris, J.L, Wood, S.G, Hughes, B.G, Sidwell, R.W, (1992). Evaluation of the antiviral activity and mode of action of anthraquinones, anthrones, and anthraquinone derivatives against human cytomegalovirus.. Recent Advances in Chemotherapy, 1, 1772-1773.
        • Barnard, D., Huffman, J.H, Morris, J.L, Wood, S.G, Hughes, B.G, Sidwell, R.W, (1992). Evaluation of the antiviral activity of anthraquinones, anthrones and anthraquinone against human cytomegalovirus. Antiviral Research/Elsevier, 17:1, 63-77.
        • Barnard, D., Johnson, F.B, (1992). Topographical analysis of the ADV-G virion using monoclonal antibodies. Archives of Virology/Springer Verlag, 127:1-4, 271-289.
        • Sidwell, R.W, Huffman, J.H, Barnard, D., Pifat, D.Y, (1989). Effects of ribamidine, a 3-carboxamidine derivative of ribavirin on experimentally-induced Phlebovirus infections. Antiviral Research/Elsevier, 10:4-5, 193-208.
        • Sidwell, R.W, Huffman, J.H, Barnard, D., Reist, E.J, (1989). Effect of phosphonic acid analogs of acyclovir and ganciclovir on in vitro cytomegalovirus infections. Nucleosides, Nucleotides and Nucleic Acids/Taylor & Francis , 8:5, 833-836.
        • Barnard, D., (1989). The effects of human cytomegalovirus (HCMV) inhibitory agent, 9-(3-phosphono-1-'hydroxymethyl-1'-propyloxymethyl)guanine (SR3745), on macromolecular synthesis and in vitro antiviral activity in human diploid cells. The Pharmacologist/ASPET, 31, 166.
        • Barnard, D., Farnes, K., Richards, D.F, Richards, G.F, Johnson, F.B, (1986). A new chlamydia transport medium used for transport of herpes simplex viruses. Journal of Clinical Microbiology/ASM Press, 24:5, 692-695.
        • Barnard, D., Johnson, F.B, Richards, D.F, (1985). Comparison of an avidin-biotin immunoassay with three commercially available immunofluorescence kits for typing of herpes simplex virus. Journal of Clinical Pathology/BMJ Pub. Group, 38:10, 1158-1162.
        • Professional Journal

        • Barnard, D., Li, J.K, (2011). Commentary on Epstein-Barr virus, the immune system, and associated diseases. Frontiers in Microbiology, 2, 28. doi: doi:10:3389/fmicrb.2011.00028
        • Ellis, L.C, Jackson, M.K, Barnard, D., (1996). Aleutian Disease: How it is spread and possible treatments.. Blue Book of Farming, 18-20. *
        • Public or Trade Journal

        • Sidwell, R.W, Huffman, J.H, Barnard, D., Smee, D.F, Warren, R.P, Kende, M., Huggins, J.W, (1995). Murine Punta Toro virus infection: a potential model for study of Hantavirus inhibitors. Inter Antiviral News/International Medical Presss, 3, 33-36. *

        * Has not been peer reviewed

        Publications - Literary Journal

          * Has not been peer reviewed

          Publications - MultiMedia

            * Has not been peer reviewed

            Publications - Technical Reports

              Research Reports

            • Smee, D., Barnard, D., Jones, S.M, (2016). Activities of JNJ63623872 and oseltamivir against influenza A H1N1pdm and H3N2 virus infections in mice. Antiviral Research
            • Warfield, K.L, Barnard, D., Enterlein, S.G, Smee, D., Khaliq, M., Sampath, A., Callahan, M.V, Ramstedt, U., Day, C.W, (2016). The iminosugar UV-4 is a broad inhibitor of influenza A and B viruses ex vivo and in mice. Viruses
            • Morrey, J.D, Barnard, D., Smee, D., Gowen, B., (2009). Annual Report NO1-AI-15435, NIAID, NIH. Animals Models of Human Experimental Viral Infections for Evaluation of Experimental Therapies.
            • Smee, D., Barnard, D., Morrey, J.D, Gowen, B., Julander, J., (2009). Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Morrey, J.D, Barnard, D., Morrey, J.D, Smee, D., Gowen, B., (2009). Semi-Annual Report NO1-AI-15435, NIAID, NIH. Animals Models of Human Experimental Viral Infections for Evaluation of Experimental Therapies.
            • Smee, D., Barnard, D., Morrey, J.D, Gowen, B., Julander, J., (2009). Semi-Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Morrey, J.D, Barnard, D., Smee, D., Gowen, B., (2008). Annual Report NO1-AI-15435, NIAID, NIH. Animals Models of Human Experimental Viral Infections for Evaluation of Experimental Therapies.
            • Morrey, J.D, Barnard, D., Smee, D., Gowen, B., (2008). Annual Report NO1-AI-15435, NIAID, NIH. Animals Models of Human Experimental Viral Infections for Evaluation of Experimental Therapies.
            • Smee, D., Barnard, D., Morrey, J.D, Gowen, B., Julander, J., (2008). Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Morrey, J.D, Barnard, D., Morrey, J.D, Smee, D., Gowen, B., (2008). Semi-Annual Report NO1-AI-15435, NIAID, NIH. Animals Models of Human Experimental Viral Infections for Evaluation of Experimental Therapies.
            • Smee, D., Barnard, D., Morrey, J.D, Gowen, B., Julander, J., (2008). Semi-Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Morrey, J.D, Barnard, D., Smee, D., Gowen, B., (2007). Annual Report NO1-AI-15435, NIAID, NIH. Animals Models of Human Experimental Viral Infections for Evaluation of Experimental Therapies.
            • Smee, D., Barnard, D., Morrey, J.D, Gowen, B., Julander, J., (2007). Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Morrey, J.D, Barnard, D., Smee, D., Gowen, B., (2007). Semi-Annual Report NO1-AI-15435, NIAID, NIH. Animals Models of Human Experimental Viral Infections for Evaluation of Experimental Therapies.
            • Smee, D., Barnard, D., Morrey, J.D, Gowen, B., Julander, J., (2007). Semi-Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., (2006). Annual Report NO1-AI-15435, NIAID, NIH. Animals Models of Human Experimental Viral Infections for Evaluation of Experimental Therapies.
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., Julander, J., (2006). Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., Julander, J., (2006). Semi Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., (2006). Semi-Annual Report NO1-AI-15435, NIAID, NIH. Animals Models of Human Experimental Viral Infections for Evaluation of Experimental Therapies.
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., (2005). Annual Report NO1-AI-15435, NIAID, NIH. Animals Models of Human Experimental Viral Infections for Evaluation of Experimental Therapies.
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., (2005). Semi Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., (2005). Semi-Annual Report NO1-AI-15435, NIAID, NIH. Animals Models of Human Experimental Viral Infections for Evaluation of Experimental Therapies.
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., (2004). Annual Report NO1-AI-15435, NIAID, NIH. Animals Models of Human Experimental Viral Infections for Evaluation of Experimental Therapies.
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., (2004). Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., (2004). Semi Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., (2004). Semi-Annual Report NO1-AI-15435, NIAID, NIH. Animals Models of Human Experimental Viral Infections for Evaluation of Experimental Therapies.
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., (2003). Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., (2003). Semi Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., (2002). Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., (2002). Semi Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., (2001). Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., (2001). Semi Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., (2000). Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., (2000). Semi Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., (1999). Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., (1999). Semi Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .

            * Has not been peer reviewed

            Publications - Translations & Transcripts

              Publications - Other

                Other

              • Barnard, D., (2008). Select Agent Standard Operating Procedure Manual for the Select Agent Laboratory in LARC 146.
              • Ellis, L.C, Jackson, M.K, Morrey, J.D, Barnard, D., Li, Z.-, (1993). Aleutian disease: Current status and developments. Blue Book of Farming *
              • Jackson, M.K, Ellis, L.C, Morrey, J.D, Barnard, D., (1992). Early detection of Aleutian disease virus in mink by polymerase chain reaction. Norwegian Journal of Agricultural Science/Norwegian Agricultural Advisory Centre *

              * Has not been peer reviewed

              Graduate Students Mentored

              Jason Roth, Animal, Dairy and Veterinary Sciences, January 2003 - May 2010
              Kie-Hoon Jung, Biology, January 1998 - May 2004
              Louise Silvers, Other, February 1998 - December 2002