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S. Clay Isom

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Animal, Dairy and Veterinary Sciences

Developmental Genetics & Epigenetics

Associate Professor

Educational Background

PhD, Animal Sciences, University of Missouri, 2006
BS, Animal Science, Utah State University, 2000


Biography

Born & raised in Lyman, Wyoming.

Teaching Interests

Reproductive physiology

Research Interests

epigenetics, embryo/environment interactions, preimplantation embryo development, oocyte quality


Contact Information

Go toOffice Location: AGRS 243
DialPhone: 435-797-8114
SendEmail: clay.isom@usu.edu

Awards

Teacher of the Year, 2016

ADVS Department

Teacher of the Year, 2016

CAAS

Teacher of the Year, 2015

ADVS Department

Graduate Research Mentor of the Year, 2014

ADVS

Graduate Research Mentor of the Year, 2014

CAAS

Dorris D. & Christine M. Brown Graduate Research Fellowship, 2003

University of Missouri–Columbia

USDA National Needs Travel Award, 2003

University of Missouri–Columbia

USDA/CSREES National Needs Graduate Student Fellowship, 2000

University of Missouri–Columbia

University Club Scholarship, 1997

Utah State University

University Club Scholarship, 1993

Utah State University

    Publications - Books & Book Chapters

      * Has not been peer reviewed

      Publications - Fact Sheets

        * Has not been peer reviewed

        Publications - Curriculum

          * Has not been peer reviewed

          Publications - Journal Articles

            Academic Journal

          • Li, Q., Suasnavas, E., Heywood, S., Xiao, L., Zhou, A., Isom, S., (2015). Biochemical, biophysical and genetic changes of porcine trophoblast-derived stem-like cells during differentiation as evaluated using Raman microspectroscopy, Atomic force microscopy and quantitative polymerase chain reaction. genesis , The Journal of Genetics and Development , 53:12, 749-761. doi: doi: 10.1002/dvg.22907
          • Li, Q., Suasnavas, E., Xiao, L., Heywood, S., Qi, X., Zhou, A., Isom, S., (2015). Label-Free and Non-Invasive Monitoring of Porcine Trophoblast Derived Cells: Differentiation in Serum and Serum-Free Media. Journal of Biophotonics, 8:8, 638-645. doi: doi:10.1002/jbio.201400062
          • Cox, L., Vanderwall, D.K, Parkinson, K.C, Sweat, L., Isom, S., (2015). Expression profiles of select genes in cumulus-oocyte complexes from young and aged mares. Reproduction Fertility & Development, doi: doi: 10.1071/RD14446
          • Sanz-Fernandez, M., Johnson, J., Abuajamieh, M., Stoakes, S., Seibert, J., Cox, L., Kahl, S., Elsasser, T., Ross, J., Isom, S., Rhoads, R., Baumgard, L., (2015). . Effects of heat stress on carbohydrate and lipid metabolism in growing pigs. Physiol Rep, 3:2, doi: doi: 10.14814/phy2.12315
          • Suasnavas, E., Heywood, S., Ward, A., Cox, L., O'Grady, M., Zhao, Y., Isom, S., (2015). Isolation and characterization of trophoblast-derived stem-like cells from peri-implantation porcine embryos. Animal Reproduction Science, 154, 128-141. doi: doi: 10.1016/j.anireprosci.2015.01.012
          • Saunders, G., Stevens, J.R, Isom, S., (2014). A shortcut for multiple testing on the directed acyclic graph of Gene Ontology. BMC Bioinformatics, 15:349, doi: DOI: 10.1186/s12859-014-0349-3
          • Suasnavas, E., Heywood, S., Ward, A., Cox, L., O'Grady, M., Zhao, Y., Isom, S., Characterization of trophoblast-derived stem-like cells from peri-implantation porcine embryos.. Animal Reproduction Science
          • Isom, S., Stevens, J.R, Li, R., Spollen, W., Cox, L., Spate, L., Murphy, C., Prather, R., (2013). Transcriptional profiling by RNA-Seq of peri-attachment porcine embryos generated using a variety of assisted reproductive technologies (ART). Physiol Genomics, 45:14, 577-589. doi: 10.1152/physiolgenomics.00094.2012
          • Morrill, B.H, Cox, L., Ward, A., Heywood, S., Isom, S., Targeted DNA methylation analysis by high throughput sequencing in porcine peri-attachment embryos. Journal of Reproduction and Development
          • Isom, S., Li, R., Whitworth, K.M, Prather, R.S, Timing of First Embryonic Cleavage Is a Positive Indicator of the In Vitro Developmental Potential of Porcine Embryos Derived From In Vitro Fertilization, Somatic Cell Nuclear Transfer and Parthenogenesis. Molecular Reproduction and Development, doi: 10.1002/mrd.22013
          • Zhao, M., Whitworth, K., Lin, H., Zhang, X., Isom, S., Dobbs, K., Bauer, B., Prather, R., (2010). Porcine skin-derived progenitor (SKP) spheres and neurospheres: Distinct "stemness" identified by microarray analysis. Cell Reprogram, 12:3, 329-345.
          • Isom, S., Prather, R., Rucker, E., (2009). Enhanced developmental potential of heat shocked porcine parthenogenetic embryos is related to accelerated mitogen-activated protein kinase dephosphorylation. Society of Reproductive and Fertility Supplement, 21:7, 892-900.
          • Prather, R., Ross, J., Isom, S., Green, J., (2009). Transcriptional, post-transcriptional and epigenetic control of porcine oocyte maturation and embryogenesis. Society of Reproductive and Fertility Supplement, 66, 165-176.
          • Isom, S., Lai, L., Prather, R., Rucker, E., (2009). Response of porcine cleavage-stage embryos to heat shock depends on timing of stressor application relative to oocyte activation. Molecular Reproduction & Development, 76:6, 548-554.
          • Zhao, M., Isom, S., Lin, H., Hao, Y., Zhao, J., Whyte, J., Doggs, K., Zhang, Y., Prather, R., (2009). Tracing the stemness of porcine skin derived progenitors (pSKP) back to specific marker gene expression. Cloning Stem Cells, 11:1, 111-122.
          • Li, R., Whitworth, K., Lai, L., Wax, D., Spate, L., Murphy, C., Rieke, A., Isom, S., Hao, Y., Zhong, Z., Katayama, M., Schatten, H., Prather, R., (2007). Concentration and composition of free amino acids and osmolalities of porcine oviductal and uterine fluid and their effects on development of porcine embryos. Molecular Reproduction & Development, 74, 1228-1235.
          • Isom, S., Prather, P., Rucker III, E., (2007). Heat stress-induced apoptosis in porcine in vitro fertilized and parthenogenetic preimplantation-stage embryos. Molecular Reproduction & Development, 74, 574-581.
          • Li, R., Murphy, C., Spate, L., Wax, D., Isom, S., Rieke, A., Walters, E., Samuel, M., Prather, R., (2007). Production of piglets after cryopreservation of embryos using a centrifugation-based method for delipation without micromanipulation. Molecular Reproduction & Development, 74, 1228-1235.

          * Has not been peer reviewed

          Publications - Literary Journal

            * Has not been peer reviewed

            Publications - MultiMedia

              Web

            • Isom, S., Spollen, W., Green, J., Springer, G., Prather, R., (2010). Transcriptional Profiling of Day 12 Porcine Embryonic Disc and Trophectoderm Samples Using Ultra-Deep Sequencing Technologies. Molecular Reproduction & Development
            • Bauer, B., Isom, S., Spate, L., Whitworth, K., Spollen, W., Blake, S., Springer, G., Murphy, C., Prather, R., (2010). Transcriptional Profiling Identifies Differences in mRNA Transcript Abundance in In Vivo Vs. In Vitro Cultured Porcine Preimplantation Embryos. Biology of Reproduction

            * Has not been peer reviewed

            Publications - Technical Reports

              * Has not been peer reviewed

              Publications - Translations & Transcripts

                Publications - Other

                  Other

                * Has not been peer reviewed

                Scheduled Teaching

                ADVS 6800 - Graduate Student Seminar, Spring 2017

                ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2016

                ADVS 6800 - Graduate Student Seminar, Spring 2016

                ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2015

                ADVS 6900 - Special Problems, Fall 2015

                ADVS 6800 - Graduate Student Seminar, Spring 2015

                ADVS 6200 - Physiology of Reproduction, Fall 2014

                ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2014

                ADVS 6800 - Graduate Student Seminar, Spring 2014

                ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2013

                ADVS 6200 - Physiology of Reproduction, Fall 2012

                ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2012

                ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2012

                ADVS 4200 - Physiology of Reproduction and Lactation, Fall 2012

                ADVS 4200 - Physiology of Reproduction and Lactation, Spring 2012

                ADVS 4200 - LABORATORY, Spring 2011

                ADVS 4200 - LABORATORY, Spring 2011

                ADVS 4200 - PHYL OF REPROD/LACTN (CI), Spring 2011

                ADVS 4200 - Physiology of Reprodution and Lactation, Spring 2011

                AG 422 - Physiology of Reproduction, 2007


                Graduate Students Mentored

                Laura Moley, Animal, Dairy and Veterinary Sciences
                Sameer Alhojaily, Animal, Dairy and Veterinary Sciences
                Yuanfeng Zhao, Animal, Dairy and Veterinary Sciences
                Edison Suasnavas, Animal, Dairy and Veterinary Sciences, September 2010