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Zhongde Wang

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Animal, Dairy and Veterinary Sciences

Transgenics, Molecular Biology, Stem Cell Research

Professor

Contact Information

Go toOffice Location: USTAR room 305k
DialPhone: 435-797-9668
SendEmail: zonda.wang@usu.edu


Educational Background

Nuclear reprogramming by somatic cell nuclear transfer, (Embryonic stem cells and genetic engineering), Massachusetts Institute of Technology, 2004
PhD, Molecular and Cellular Biology, University of Massachusetts at Amherst, 2000
Towards the isolation of esterase and amidase catalytic antibodies: Examination of germinal center diversity by cloning and sequence analysis of genes encoding monoclonal antibodies elicited by a transition state analogue

Expertise

Genome Engineering, Epigenetics and Stem Cells // Program goals: Developing novel genome engineering tools for improving livestock (e.g. Mastitis resistance) and for creating transgenic animal models for human diseases; Establish embryonic stem cells from livestock species and from hamsters.


Biography

Dr. Zhongde Wang is a professor in the Department of Animal, Dairy and Veterinary Sciences at Utah State University. In addition to his academic appointment, Dr. Wang is also the President and Chief Scientific Officer and co-founder of Auratus Bio, a biotech company specialized in animal genetic engineering. Dr. Wang received his Ph.D. degree in molecular and cellular biology from University of Massachusetts at Amherst in 2000 and did his postdoctoral training at the Whitehead Institute/Massachusetts Institute of Technology.


Teaching Interests

Metabolic syndromes, biotechnology, and stem cells

Research Interests

Dr. Wang’s research team employs modern genome engineering tools (such as CRISPR/Cas9) and assisted reproduction technologies (such as IVF, ICSI, and somatic cell nuclear transfer or cloning) to create genetically engineered animal models of human diseases. The Wang laboratory is the first to succeed in developing gene targeting tools in the golden Syrian hamster. His laboratory is also actively pursuing a better understanding of the epigenetics of stem cells. Current projects in Wang’s laboratory include genetic engineering in golden Syrian hamsters to create animal models of human disease. His laboratory is also actively engaging in research activities in the development of genetically engineered goats and sheep as animal models of cardiovascular diseases, lung cancer, and cystic fibrosis. The Wang laboratory is also studying embryonic stem (ES) cells and induced pluripotent stem (iPS) cells from important farm animal species. Another research focus in the Wang laboratory is by employing immunological and genetic approaches to understand and improve mastitis resistance in dairy cattle. We are always looking for highly motivated, ambitious, creative, and hardworking individuals to join the lab for postdoctoral and MS/PhD trainings. If you think you have these qualities, please contact Dr. Wang directly at zonda.wang@usu.edu

Awards

CAAS Faculty Researcher of the Year, 2017

ADVS Faculty Researcher of the Year Award, 2017

Lalor Foundation Postdoctoral Fellowships , 2003

Lalor Foundation

Lalor Foundation Postdoctoral Fellowships , 2002

Lalor Foundation

Publications - Abstracts

Publications - Books & Book Chapters

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Publications - Fact Sheets

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    Publications - Curriculum

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      Publications - Journal Articles

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      Publications - Literary Journal

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        Publications - MultiMedia

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          Publications - Technical Reports

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            Publications - Translations & Transcripts

              Publications - Other

                Other

              • Wang, Z., (2016). Correction: STAT2 Knockout Syrian Hamsters Support Enhanced Replication and Pathogenicity of Human Adenovirus, Revealing an Important Role of Type I Interferon Response in Viral Control.. PLoS pathogens
              • Polejaeva, I., Wang, Z., Hu, S., Ranjan, R., Davies, C., Thomas, A., White, K.L, (2015). Method for transgenic bovidae expressing cardiac fibrosis and associated pathology. United States Patent Application Publication *

              * Has not been peer reviewed

              Graduate Students Mentored

              Joseph Howes, Animal, Dairy and Veterinary Sciences, September 2017
              Nick Robl, Animal, Dairy and Veterinary Sciences, September 2016
              Jinxin Miao, Other, September 2015
              Dane Rasmussen, Animal, Dairy and Veterinary Sciences, September 2013
              Jacqueline LaRose, Animal, Dairy and Veterinary Sciences, September 2012