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Justin Julander

Profile Picture

Animal, Dairy and Veterinary Sciences

Virology, Antiviral Research

Research Associate Professor

Contact Information

Office Hours: 9:00AM - 5:00PM
Go toOffice Location: VSB 305
DialPhone: 435-797-7215
SendEmail: justin.julander@usu.edu

Awards

Graduate Research Mentor of the Year, 2017

ADVS department

Hightlighted article, 2016

Antiviral Research

Highlighted Articles in Antiviral Research, 2014

Elsevier

Publications - Abstracts

    Publications - Books & Book Chapters

      Books

    • Julander, J., Mutton, N., Birch, P., (2013). The complete Children's python: a comprehensive guide to the natural history, care, and breeding of Antaresia species. ECO/ Serpent's Tale *
    • Julander, J., Mutton, N., (2011). The Complete Carpet Python: a comprehensive guide to the natural history, care, and breeding of the Morelia spilota complex. ECO herpetological publishing and distribution *
    • Book Chapters

    • Dagley, A., Julander, J., (2013). A mouse model of chikungunya virus with utility in antiviral studies: Antiviral Methods and Protocols. Springer
    • Julander, J., (2009). Antiviral treatment of flaviviruses: Antiviral Research: strategies in antiviral drug discovery. ASM Press

    * Has not been peer reviewed

    Publications - Fact Sheets

      * Has not been peer reviewed

      Publications - Curriculum

        * Has not been peer reviewed

        Publications - Journal Articles

          Academic Journal

        • Clancy, C.S, Van Wettere, A., Morrey, J.D, Julander, J., (2018). Coitus-Free Sexual Transmission of Zika Virus in a Mouse Model.. Scientific reports, 8:1, 15379.
        • Yun, S., Song, B., Frank, J.C, Julander, J.G, Olsen, A.L, Polejaeva, I.A, Davies, C.J, White, K.L, Lee, Y., (2018). Functional genomics and immunologic tools: the impact of viral and host genetic variations on the outcome of Zika virus infection. Viruses, 10:8, E422. doi: 10.3390/v10080422
        • Julander, J., Siddharthan, V., Park, A.H, Preston, E., Mathur, P., Bertolio, M., Wang, H., Zukor, K., Van Wettere, A., Sinex, D.G, Morrey, J.D, (2018). Consequences of in utero exposure to Zika virus in offspring of AG129 mice.. Scientific reports, 8:1, 9384.
        • Clancy, C.S, Van Wettere, A., Siddharthan, V., Morrey, J.D, Julander, J., (2018). Comparative Histopathologic Lesions of the Male Reproductive Tract during Acute Infection of Zika Virus in AG129 and Ifnar−/− Mice. The American Journal of Pathology, 188:4, 904 - 915.
        • Julander, J.G, Siddharthan, V., Evans, J., Taylor, R., Tolbert, K., Apuli, C., Stewart, J., Collins, P., Gebre, M., Neilson, S., Van Wettere, A., Lee, Y., Sheridan, W.P, Morrey, J.D, Babu, Y., (2017). Efficacy of the broad-spectrum antiviral compound BCX4430 against Zika virus in cell culture and in a mouse model. Antiviral Research (Antiviral Res), 137, 14-22. doi: 10.1016/j.antiviral.2016.11.003
        • Yun, S., Song, B., Frank, J.C, Julander, J.G, Polejaeva, I.A, Davies, C.J, White, K.L, Lee, Y., (2016). Complete genome sequences of three historically important, spatiotemporally distinct, and genetically divergent strains of Zika virus: MR-766, P6-740, and PRVABC-59. Genome Announcements (Genome Announc), 4:4, e00800-16. doi: 10.1128/genomeA.00800-16
        • Yun, S., Song, B., Frank, J.C, Julander, J.G, Polejaeva, I.A, Davies, C.J, White, K.L, Lee, Y., (2016). Complete genome sequences of three historically important, spatiotemporally distinct, and genetically divergent strains of Zika virus: MR-766, P6-740, and PRVABC-59. Genome Announcements (Genome Announc), 4:4, e00800-16. doi: 10.1128/genomeA.00800-16
        • Dagley, A., Ennis, J., Turner, J.D, Rood, K., Van Wettere, A., Gowen, B., Julander, J., (2014). Protection against Chikungunya virus induced arthralgia following prophylactic treatment with adenovirus vectored interferon (mDEF201). Antiviral Research, 108, 1-9. doi: 10.1016/j.antiviral.2014.05.004
        • Julander, J., Kesler, K., Van Wettere, A., Morrey, J.D, Smee, D., (2014). The use of plethysmography in determining the severity of lung pathology in a mouse model of minimally lethal influenza virus infection. Antiviral Research, 108, 10-13. doi: 10.1016/j.antiviral.2014.05.002
        • Chung, D.H, Jonsson, C.B, Tower, N.A, Chu, Y.K, Sahin, E., Golden, J.E, Noah, J.W, Shroeder, C.E, Sotsky, J.B, Sosa, M.I, Cramer, D.E, McKellip, S.N, Rasmussen, L., White, E.L, Schmaljohn, C.S, Julander, J., Smith, J.M, Filone, C.M, Connor, J.H, Sakurai, Y., Davey, R.A, (2014). Discovery of a novel compound with anti-venezuelan equine encephalitis virus activity that targets the nonstructural protein 2. PLoS Pathog., 10:6, e1004213. doi: 10.1371/journal.ppat.1004213
        • Julander, J., Thibodeaux, B., Morrey, J.D, Roehrig, J.T, Blair, C.D, (2014). Humanized monoclonal antibody 2C9-cIgG has enhanced efficacy for yellow fever prophylaxis and therapy in an immunocompetent animal model. Antiviral Research, 103, 32-38. doi: 10.1016/j.antiviral.2013.12.011
        • Wu, C.C, Crain, B., Yao, S., Sabet, M., Lao, F.S, Tawatao, R., Chan, M., Smee, D., Julander, J., Cottam, H.B, Guiney, D.G, Corr, M., Carson, D.A, Hayashi, T., (2014). Innate immune protection of infectious disease by pulmonary administration of phospholipid conjugated TLR7 ligands. Journal of Innate Immunity, 6:3, 315-324.
        • Wang, H., Siddharthan, V., Kessler, K.K, Hall, J.O, Motter, N.E, Julander, J., Morrey, J.D, (2013). Fatal neurological respiratory insufficiency is common among viral encephalitides. The Journal of Infectious Diseases, 208:4, 573-83.
        • Julander, J., Experimental therapies for yellow fever. Antiviral Research, 97:2, 169-179. doi: S0166-3542(12)00281-1. 10.1016/j.antiviral.2012.12.002
        • Nguyen, J.T, Smee, D., Barnard, D., Julander, J., Gross, M., De Jong, M., Went, G.T, (2012). Efficacy of combined therapy with amantadine, oseltamivir, and ribavirin in vivo against susceptible and amantadine-resistant influenza A viruses. PLoS ONE , 7(1): e31006, doi: 10.1371/journal.pone.0031006
        • Smee, D., Julander, J., Tarbet, B., Gross, M., Nguyen, J., (2012). Treatment of oseltamivir-resistant influenza A (H1N1) virus infections in mice with antiviral agents. Antiviral Research, 96, 13-20.
        • Julander, J., Hagloch, J., Latimer, S., Motter, N., Dagley, A., Barnard, D., Smee, D., Morrey, J.D, (2011). Use of plethysmography in assessing the efficacy of antivirals in a mouse model of pandemic influenza A virus. Antiviral Research, 92:2, 228-36.
        • Zasloff, M., Adams, A., Beckerman, B., Campbell, A., Han, Z., Luijten, E., Meza, I., Julander, J., Mishra, A., Qu, W., Taylor, J.M, Weaver, S.C, Wong, G.C, (2011). Squalamine as a broad-spectrum systemic antiviral agent with therapeutic potential. Proc Natl Acad Sci USA, 108:38, 15978-83.
        • Julander, J., Trent, D.W, Monath, T.P, (2011). Immune correlates of protection against yellow fever determined by passive immunization and challenge in the hamster model. Vaccine, 29:35, 6008-16.
        • Julander, J., Perry, S.T, Shresta, S., (2011). Important advancements in the field of anti-dengue virus research. Antivir. Chem. Chemother., 21:3, 105-16.
        • Gowen, B., Julander, J., London, N.R, Wong, M.H, Larson, D., Morrey, J.D, Li, D.Y, Bray, M., (2010). Assessing changes in vascular permeability in a hamster model of viral hemorrhagic fever. Virol. J., 7, 240.
        • Gowen, B., Julander, J., London, N.R, Wong, M.H, Larson, D., Morrey, J.D, Li, D.Y, Bray, M., (2010). Assessing changes in vascular permeability in a hamster model of viral hemorrhagic fever. Virol. J., 7:240, 1-13.
        • Lam, A.M, Murakami, E., Espiritu, C., Steuer, H.M, Niu, C., Keilman, M., Bao, H., Zennou, V., Bourne, N., Julander, J., Morrey, J.D, Smee, D., Frick, D.N, Heck, J.A, Wang, P., Nagarathnam, D., Ross, B.S, Sofia, M.J, Otto, M.J, Furman, P.A, (2010). PSI-7851, a pronucleotide of beta-D-2'-fluro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication. Antimicrob. Agents Chemother., 54:8, 3187-3196.
        • Julander, J., Jha, A.K, Choi, J.A, Jung, K.H, Smee, D., Morrey, J.D, Chu, C.K, (2010). Efficacy of 2'-C-methylcytidine against yellow fever virus in cell culture and in a hamster model. Antiviral Res., 86:3, 261-267.
        • Monath, T.P, Lee, C.K, Julander, J., Brown, A., Beasley, D.W, Watts, D.M, Hayman, E., Guertin, P., Makowiecki, J., Crowell, J., Levesque, P., Bowick, G.C, Morin, M., Fowler, E., Trent, D.W, (2010). Inactivated yellow fever 17D vaccine: development and nonclinical safety, immunogenicity and protective activity. Vaccine, 28:22, 3827-3840.
        • Julander, J., Smee, D., Morrey, J.D, Furuta, Y., (2009). Effect of T-705 treatment on western equine encephalitis in a mouse model. Antiviral Res., 82:3, 169-171.
        • Julander, J., (2009). Effect of T-705 treatment on western equine encephalitis in a mouse model. Antivirial Res., 82, 169-71.
        • Julander, J., (2009). T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections. Antivirial Res., 82, 95-102.
        • Furuta, Y., Takahashi, K., Shiraki, K., Sakamoto, K., Smee, D., Barnard, D., Gowen, B., Julander, J., Morrey, J.D, (2009). T-705 (favipiravir) and related compounds: novel broad-spectrum inhibitors of RNA viral infections. Antiviral Res, 82:3, 95-102.
        • Nair, V., Chi, G., Shu, Q., Julander, J., Smee, D., (2009). A heterocyclic molecule with significant activity against dengue virus. Bioorg. Med. Chem. Lett., 19:5, 1425-1427.
        • Nair, V., Chi, G., Shu, Q., Julander, J., Smee, D., (2009). A heterocyclic molecule with significant activity against dengue virus. Bioorg. Med. Chem. Lett., 19:5, 1425-1427.
        • Julander, J., Shafer, K., Smee, D., Morrey, J.D, Furuta, Y., (2009). Activity of T-705 in a hamster model of yellow fever virus infection in comparison with a chemically related compound T-1106. Antimicrob. Agents Chemother., 53:1, 202-209.
        • Julander, J., Shafer, K., Smee, D., Morrey, J.D, Furuta, Y., (2009). Activity of T-705 in a hamster model of yellow fever virus infection in comparison with a chemically related compound T-1106. Antimicrob. Agents Chemother., 53:1, 202-209.
        • Julander, J., Bowen, R.A, Rao, J.R, Day, C., Shafer, K., Smee, D., Morrey, J.D, Chu, C.K, (2008). Treatment of Venezuelan equine encephalitis virus infection with (-)-carbodine. Antiviral Res., 80:3, 309-315.
        • Julander, J., Bowen, R.A, Rao, J.R, Day, C., Shafer, K., Smee, D., Morrey, J.D, Chu, C.K, (2008). Treatment of Venezuelan equine encephalitis virus infection with (-)-carbodine. Antiviral Res., 80:3, 309-315.
        • Julander, J., Skirpstunas, R., Siddharthan, V., Shafer, K., Hoopes, J.D, Smee, D., Morrey, J.D, (2008). C3H/HeN mouse model for the evaluation of antiviral agents for the treatment of Venezuelan equine encephalitis virus infection. Antiviral Res., 78:3, 230-241.
        • Julander, J., Skirpstunas, R., Siddharthan, V., Shafer, K., Hoopes, J.D, Smee, D., Morrey, J.D, (2008). C3H/HeN mouse model for the evaluation of antiviral agents for the treatment of Venezuelan equine encephalitis virus infection. Antiviral Res., 78:3, 230-241.
        • Selvam, P., Vijayalakshimi, P., Smee, D., Gowen, B., Julander, J., Day, C.W, Barnard, D., (2007). Novel 3-sulphonamido-quinazolin-4(3H)-one derivatives: microwave-assisted synthesis and evaluation of antiviral activities against respiratory and biodefense viruses.. Antiviral Chemistry and Chemotherapy/International Medical Press, 18:5, 301-5.
        • Morrey, J.D, Siddharthan, V., Olsen, A.L, Wang, H., Julander, J., Hall, J.O, Li, H., Nordstrom, J.L, Koenig, S., Johnson, S., Diamond, M.S, (2007). Defining limits of treatment with humanized neutralizing monoclonal antibody for West Nile virus neurological infection in a hamster model.. Antimicrob. Agents Chemother., 51 (7), 2396-402.
        • Julander, J., Judge, J.W, Olsen, A.L, Rosenberg, B., Shafer, K., Sidwell, R.W, (2007). Prophylactic treatment with recombinant Eimeria protein, alone or in combination with an agonist cocktail, protects mice from Banzi virus infection.. Antiviral Research, 75(1), 14-19.
        • Julander, J., Furuta, Y., Shafer, K., Sidwell, R.W, (2007). Activity of T-1106 in a hamster model of yellow fever virus infection.. Antimicrob. Agents Chemother., 51(6), 1962-6.
        • Julander, J., Siddharthan, V., Blatt, L.M, Shafer, K., Sidwell, R.W, Morrey, J.D, (2007). Effect of exogenous interferon and an interferon inducer on western equine encephalitis virus disease in a hamster model. Virology, 360:2, 454-460.
        • Julander, J., Morrey, J.D, Blatt, L.M, Shafer, K., Sidwell, R.W, (2007). Comparison of the inhibitory effects of interferon alfacon-1 and ribavirin on yellow fever virus infection in a hamster model. Antiviral Res., 73:2, 140-146.
        • Stuyver, L.J, McBrayer, T.R, Tharnish, P.M, Clark, J., Hollecker, L., Lostia, S., Nachman, T., Grier, J., Bennett, M.A, Xie, M.Y, Schinazi, R.F, Morrey, J.D, Julander, J., Furman, P.A, Otto, M.J, (2006). Inhibition of hepatitis C replicon RNA synthesis by beta-D-2'-deoxy-2'fluoro-2'-C-methylcytidine: a specific inhibitor of hepatitis C virus replication. Antiv. Chem. Chemother., 17:2, 79-87.
        • Julander, J., Winger, Q.A, Rickords, L.F, Shi, P.Y, Tilgner, M., Binduga-Gajewska, I., Sidwell, R.W, Morrey, J.D, (2006). West Nile virus infection of the placenta.. Virology, 347:1, 175-182.
        • Day, C.W, Smee, D., Julander, J., Yamshchikov, V.F, Sidwell, R.W, Morrey, J.D, (2005). Error-prone replication of West Nile virus caused by ribavirin.. Antiviral Res., 67:1, 38-45.
        • Julander, J., Winger, Q.A, Olsen, A.L, Day, C.W, Sidwell, R.W, Morrey, J.D, (2005). Treatment of West Nile virus-infected mice with reactive immunoglobulin reduces fetal titers and increased dam survival. Antiviral Res., 65:2, 79-85.
        • Morrey, J.D, Day, C.W, Julander, J., Olsen, A.L, Sidwell, R.W, Cheney, C.D, Blatt, L.M, (2004). Modeling hamsters for evaluating West Nile virus therapies.. Antiviral Res., 63:1, 41-50.
        • Iyer, R.P, Roland, A., Jin, Y., Mounir, S., Korba, B., Julander, J., Morrey, J.D, (2004). Anti-hepatitis B virus activity of ORI-9020, a novel phosphorothioate dinucleotide, in a transgenic mouse model.. Antimicrob Agents Chemother, 48:6, 2318-2320.
        • Morrey, J.D, Day, C.W, Julander, J., Blatt, L.M, Smee, D., Sidwell, R.W, (2004). Effect of interferon-alpha and interferon-inducers on West Nile virus in mouse and hamster animal models.. Antivir Chem Chemother, 15:2, 101-109.
        • Julander, J., Colonno, R.J, Sidwell, R.W, Morrey, J.D, (2003). Characterization of antiviral activity of entecavir in transgenic mice expressing hepatitis B virus.. Antiviral Res, 59:3, 155-161.
        • Julander, J., Sidwell, R.W, Morrey, J.D, (2002). Characterizing antiviral activity of adefovir dipivoxil in transgenic mice expressing hepatitis B virus. Antiviral Res., 55:1, 27-40.
        • Professional Journal

        • Richner, J.M, Himansu, S., Butler, S., Dowd, K.A, Salazar, V., Fox, J.M, Julander, J., Tang, W.W, Shresta, S., Pierson, T.C, Ciaramella, G., Diamond, M.S, (2017). A modified mRNA vaccine platform protects against Zika virus pathogenesis and minimizes antibody-dependent enhancement of Dengue virus infection. Cell, 168:6, 1114-1125.e10. doi: 10.1016/j.cell.2017.02.017
        • Guo, F., Wu, S., Julander, J., Ma, J., Zhang, X., Kulp, J., Cuconati, A., Block, T.M, Du, Y., Guo, J., Chang, J., (2016). A novel benzodiazepine compound inhibits yellow fever virus infection by specifically targeting NS4B protein. Journal of VirologyJVI.01253-16
        • Julander, J., (2016). Animal models of yellow fever and their application in clinical research. Curr. Opin. Virol., 18, 64-9. doi: 10.1016/j.coviro.2016.03.010.
        • Taylor, R., Kotian, P., Warren, T., Bavari, S., Julander, J., Dobo, S., Rose, A., El-Kattan, Y., Taubenheim, B., Babu, Y., Sheridan, W.P, (2016). BCX4430 - a broad-spectrum antiviral adenosine nucleoside analog under development for the treatment of Ebola virus disease. J. Infect. Public Health, 9:3, 220-6. doi: 10.1016/j.jiph.2016.04.002
        • Julander, J., Bantia, S., Taubenheim, B.R, Minning, D.M, Kotian, P., Morrey, J.D, Smee, D., Sheridan, W.P, Babu, Y.S, (2014). BCX4430, a novel nucleoside analog, effectively treats yellow fever in a hamster model. Antimicrobial Agents and Chemotherapy, 58:11, 6607-6614.
        • Wang, H., Siddharthan, V., Kesler, K., Hall, J.O, Motter, N.E, Julander, J., Morrey, J.D, (2013). Autonomic Deficit not the Cause of Death in West Nile Virus Neurological Disease. J Infect Dis, 204:4, 573-583.
        • Wand, H., Siddharthan, V., Kesler, K., Hall, J.O, Motter, N.E, Julander, J., Morrey, J.D, (2013). Autonomic Deficit not the Cause of Death in West Nile Virus Neurological Disease. J Infect Dis, 204:4, 573-583.
        • Julander, J., Ennis, J., Turner, J., Morrey, J.D, (2011). Treatment of yellow fever virus with an adenovirus-vectored interferon, DEF201, in a hamster model. Antimicrob. Agents Chemother., 55:5, 2067-73.

        * Has not been peer reviewed

        Publications - Literary Journal

          * Has not been peer reviewed

          Publications - MultiMedia

            * Has not been peer reviewed

            Publications - Technical Reports

              Research Reports

            • Smee, D., Barnard, D., Morrey, J.D, Gowen, B., Julander, J., (2009). Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Smee, D., Barnard, D., Morrey, J.D, Gowen, B., Julander, J., (2009). Semi-Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Smee, D., Barnard, D., Morrey, J.D, Gowen, B., Julander, J., (2008). Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Smee, D., Barnard, D., Morrey, J.D, Gowen, B., Julander, J., (2008). Semi-Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Smee, D., Barnard, D., Morrey, J.D, Gowen, B., Julander, J., (2007). Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Smee, D., Barnard, D., Morrey, J.D, Gowen, B., Julander, J., (2007). Semi-Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., Julander, J., (2006). Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .
            • Sidwell, R., Barnard, D., Morrey, J.D, Smee, D., Gowen, B., Julander, J., (2006). Semi Annual Report NO1-AI-85348, NIAID, NIH. In vitro antiviral screen for respiratory viruses. .

            * Has not been peer reviewed

            Publications - Translations & Transcripts

              Publications - Other

                * Has not been peer reviewed

                Extension

                Evaluation of Antiviral Agents in Animal Models of Viral Disease, - Ongoing
                HDTRA1-08-C-0003, - Ongoing
                Influenza work, - Ongoing
                Pharmaceutical, - Ongoing
                Screening of antiviral compounds in cell culture, - Ongoing

                Graduate Students Mentored

                Chad Clancey, Animal, Dairy and Veterinary Sciences, August 2015 - February 2019
                Makda Gebre, Animal, Dairy and Veterinary Sciences, August 2015 - May 2017
                Ashley Dagley, Animal, Dairy and Veterinary Sciences, January 2009 - November 2015